https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Improving Student Retention and Success Within the Context of Complex Lives and Diverse Circumstances https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42537 Wed 24 Aug 2022 16:04:18 AEST ]]> Galectin-3 is associated with Stage B metabolic heart disease and pulmonary hypertension in young obese patients https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42185 P<0.001). GAL3 levels were higher in MHD‐POS versus MHD‐NEG patients (7.7±2.3 versus 6.3±1.9 ng/mL, respectively; P<0.001). Both GAL3 and FSTL3 levels correlated with diastolic dysfunction and increased pulmonary artery systolic pressure but not with left ventricular mass. In multivariate models including all 3 biomarkers, only GAL3 remained associated with MHD (odds ratio: 1.30; 95% CI, 1.01–1.68; P=0.04). Conclusions: In young obese individuals without known cardiovascular disease, GAL3 is associated with the presence of preclinical MHD. GAL3 may be useful in screening for preclinical MHD and identifying individuals with increased risk of progression to obesity‐related heart failure with preserved ejection fraction.]]> Fri 26 Aug 2022 08:26:42 AEST ]]>